Synthetic BiologyCell ReportsPeer-reviewed
CAR T Cells Secreting IL18 Augment Antitumor Immunity and Increase T Cell Proliferation and Costimulation
Biliang Hu, Jiangtao Ren, Yanping Luo…·Carl H. June
This study shows that IL18-expressing CAR T cells enhance antitumor immunity, T cell proliferation, and costimulation, while reducing GVHD risk through a novel strategy.
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