Robi Tăcutu

This study shows that the composition of training data, especially negative examples, affects machine learning model performance and biological rule discovery in antibody-antigen binding.

This study investigates the similarity between transcriptional changes in healthy aging and age-related diseases to predict drugs that could reverse these common patterns.

The paper introduces scAgeCom, an atlas of age-related intercellular communication changes in 23 mouse tissues, using the scDiffCom package to analyze single-cell RNA-seq data from two consortia.

SynergyAge curates genetic and lifespan data from animal models with multiple longevity-modulating interventions to explore synergistic and antagonistic gene interactions.

The paper curates a database of senescence-associated genes and performs systems biology analyses to identify novel regulators and pathways of cellular senescence.

This paper updates the Human Ageing Genomic Resources (HAGR), presenting its five databases and their functionalities for studying ageing and longevity.

This study compares longevity-associated genes across 205 species to determine their conservation and functional roles in aging.