Author

Jes Sanddal Lindholt

Odense University HospitalORCID 0000-0001-9536-4488Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Iftikhar J. KulloiD· 2 shared Matthew J. BowniD· 2 shared Adam E. LockeiD· 1 shared Adam S. ButterworthiD· 1 shared Alex Hørby ChristenseniD· 1 shared Alicia C. Deng· 1 shared Alison J. FiniganiD· 1 shared Anders WanhaineniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Iftikhar J. KulloORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 27, 2022

Multi-ancestry GWAS deciphers genetic architecture of abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

Tanmoy Roychowdhury, Derek M. Klarin, Michael G. Levin…·Scott M. Damrauer

This study identifies 144 genetic loci associated with abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target through Mendelian Randomization and pre-clinical validation.

9 citations

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsCirculation Genomic and Precision MedicinePeer-reviewedFeb 1, 2019

Interleukin-6 Receptor Signalling and Abdominal Aortic Aneurysm Growth Rates

Ellie Paige, Marc Clément, Fabien Lareyre…·Ziad Mallat

The paper investigates the effect of the IL6R-Asp358Ala variant on AAA growth and evaluates IL-6 pathway blockade in mouse models, finding no significant growth rate reduction but improved survival with trans-signalling inhibition.

64 citationstop 2%

mousestatistical model

𝕏 PostBluesky