Author

Ellie Paige

Australian National UniversityORCID 0000-0003-0855-9872Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam S. ButterworthiD· 3 shared John DaneshiD· 3 shared Angela WoodiD· 2 shared Benjamin B. SuniD· 2 shared Clare Oliver‐WilliamsiD· 2 shared Dirk S. PauliD· 2 shared James E. PetersiD· 2 shared Praveen SurendraniD· 2 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenetics

Adam S. ButterworthORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintFeb 3, 2020

Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes

Luca Andrea Lotta, Maik Pietzner, Isobel D. Stewart…·Claudia Langenberg

This study identifies genetic associations with metabolite levels across multiple cohorts and links these variants to clinical outcomes like type 2 diabetes and macular telangiectasia type 2.

15 citations

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsCirculation Genomic and Precision MedicinePeer-reviewedFeb 1, 2019

Interleukin-6 Receptor Signalling and Abdominal Aortic Aneurysm Growth Rates

Ellie Paige, Marc Clément, Fabien Lareyre…·Ziad Mallat

The paper investigates the effect of the IL6R-Asp358Ala variant on AAA growth and evaluates IL-6 pathway blockade in mouse models, finding no significant growth rate reduction but improved survival with trans-signalling inhibition.

64 citationstop 2%

mousestatistical model

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GenomicsNaturePeer-reviewedMay 29, 2018

Consequences Of Natural Perturbations In The Human Plasma Proteome

Benjamin B. Sun, Joseph Maranville, James E. Peters…·Adam S. Butterworth

The paper identifies 1,927 genetic associations with 1,478 plasma proteins using 10.6 million DNA variants and 3,301 individuals, revealing new drug targets and safety concerns.

2,267 citationstop 1%

humanproteomics

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