Guilhem Faure

TIGRFinder annotated 6,685 TIGR arrays; cryo-EM structures show inactive RuvC domains, and E. coli reporter assays show CsTasR and MbTasA repress transcription in a guide-dependent manner.

This study shows that Lactobacillus helveticus VEL12193 promotes autophagy in vitro and in vivo through membrane vesicles, with potential applications for healthy aging.

The paper identifies cargo genes of Tn7-like transposons, revealing their role in transferring diverse genes including MGEs, defense systems, and antibiotic resistance genes.