Developmental BiologybioRxivPreprint
YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids
Servando Giráldez, Eleonora Stronati, Ling Huang…·Conchi Estarás
This study shows YAP1 is essential for proper germ layer patterning in hESCs-derived gastruloids by regulating NODAL signaling and repressing mesoendodermal differentiation.