Author

Alexandre Harlé

Centre National de la Recherche ScientifiqueORCID 0000-0001-9548-6522Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Aitor Rodríguez‐CasanovaiD· 1 shared Alexis RapiniD· 1 shared Anes Hadjadj AouliD· 1 shared Ángel Díaz‐LagaresiD· 1 shared Anne‐Marie C. DingemansiD· 1 shared Chloe Ryder· 1 shared Christophe PassotiD· 1 shared Clémence MichoniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Aitor Rodríguez‐CasanovaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genetic & Genomic MedicineJournal of Molecular DiagnosticsPeer-reviewedSep 25, 2025

Analytical Validation of a Pan-Cancer NGS Assay for In-House Liquid Biopsy Testing: An International Multicenter Study

Gaëlle Lescuyer, Alexandre Harlé, Hari Shankar Kumar…·Lea Francoise Payen

This study validates a pan-cancer NGS assay for liquid biopsy testing across multiple centers, showing high sensitivity and specificity for detecting genomic alterations in cfDNA.

3 citations

humanwhole-exome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 30, 2024

Critical assay parameters facilitating confident detection of expression changes, fusions and short variants in RNA isolated from tissue

Slawomir Kubik, Izabela Matyszczak, Nicholas R. T. Toda…·Zhenyu Xu

The paper identifies critical sequencing parameters for reliable detection of expression changes, fusions, and variants in targeted RNA sequencing of tumor samples.

DOI 10.1101/2024.10.30.621018

humanbulk RNA-seq

𝕏 PostBluesky