Author

Zhenyu Xu

Sophia Genetics (Switzerland)ORCID 0000-0002-3484-9147Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zhenyu Xu2 papers · Hangzhou Institute of Medicine, Chinese Academy of Sciences

Biology Disciplines

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Genomics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant calling· 1 Organism:virus· 1

Frequent Co-Authors

Slawomir KubikiD· 3 shared Ewan W. Smith· 2 shared Adrian Willig· 1 shared Alexandra Saitta· 1 shared Alexandre HarléiD· 1 shared Ali Si-Mohammed· 1 shared Ana Claudia MarquesiD· 1 shared Carsten TiemanniD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenomics

Slawomir KubikORCID

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3 papers

Recent·Most cited

Critical assay parameters facilitating confident detection of expression changes, fusions and short variants in RNA isolated from tissue

Slawomir Kubik, Izabela Matyszczak, Nicholas R. T. Toda, Elia Magrinelli, Pierre‐Yves Helleboid, Ewan W. Smith, Fedor Bezrukov, Chloe Ryder, Jonathan Lopez, Alexandre Harlé, Zhenyu Xu

The paper identifies critical sequencing parameters for reliable detection of expression changes, fusions, and variants in targeted RNA sequencing of tumor samples.

bioRxiv · Oct 30, 2024 · PreprintCancer Biology

Mutational hotspot in the SARS-CoV-2 Spike protein N-terminal domain conferring immune escape potential

Slawomir Kubik, Nils Arrigo, Jaume Bonet, Zhenyu Xu

Viruses · Oct 20, 2021Peer-reviewedGenomics

Guidelines for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples

Slawomir Kubik, Ana Claudia Marques, Xiaobin Xing, Janine Silvery, Claire Bertelli, Flavio De Maio, Spyros Pournaras, Tom Burr, Yannis Duffourd, Helena Siemens, Chakib Alloui, Lin Ye Song, Yvan Wenger, Alexandra Saitta, Morgane Macheret, , Zhenyu Xu

This study provides guidelines for accurate SARS-CoV-2 genotyping using amplicon-based sequencing, showing that at least 1000 viral genomes are needed to reliably detect variants at 10% frequency.

Clinical Microbiology and Infection · Apr 2, 2021Peer-reviewedGenomics