Cancer BiologybioRxivPreprint
The Y chromosome gene KDM5D restrains CD8+ T cell antitumor immunity through TCR and cholesterol-exhaustion programs
Jiexi Li, Chi Yin Ching, Aviad Ben‐Shmuel…·Ronald Anthony DePinho
This study identifies KDM5D on the Y chromosome as a suppressor of CD8+ T cell antitumor immunity in males, linking it to TCR and cholesterol-exhaustion programs.