Anders Poulsen Charmouh

The paper introduces a method to estimate gene conversion tract length and rate from PacBio HiFi data, showing low visibility of NCO events in human sperm due to low SNV density.

This study uses long-read sequencing to analyze gene conversion and crossover events in human, chimpanzee, and gorilla testes and sperm, revealing species-specific patterns and GC bias in gene conversion.

The paper evaluates a method for inferring the distribution of fitness effects by adding a parameter to account for strongly deleterious mutations, showing it can improve model fit but may introduce biases.