Claudia H. Kawas

This study uses bulk RNA-seq to analyze transcriptional changes in the middle temporal gyrus across Alzheimer's disease and aging, identifying distinct gene expression patterns and pathways associated with each condition.

The paper identifies molecular programs coordinated with NPTX2 that distinguish cognitive resilience in AD pathology from non-pathological cognition and AD.

This study examines the relationship between white matter hyperintensities, medial temporal lobe volumes, and memory in older adults, finding that occipital hyperintensities are linked to reduced subregional volumes and worse memory performance.

This study identifies JADE1 as a novel genetic factor in tauopathy through genome-wide association and functional validation in human and Drosophila models.