Michael A. Yassa

This study examines how anhedonia and early-life unpredictability interact to influence threat-reward decision-making in humans.

This paper tests whether memory discrimination is supported by lossy compression or expansion of neural codes, finding that greater lossiness predicts better performance in a memory task.

This study quantifies age-related changes in brain spatial geometry using structural MRIs and links these changes to cognitive impairments.

The paper defines a histology-informed MRI mask for the human paraventricular nucleus of the thalamus, showing spatial overlap with existing masks but with additional posterior voxels and consistent functional connectivity patterns.

This study examines how early-life unpredictability affects hippocampal and amygdala responses to novelty in adolescents, finding sex-specific differences in brain activation and functional connectivity.

This study investigates how race affects functional brain network configurations during face recognition using graph-theoretical analysis, finding race-related differences in local efficiency and network support for same- and other-race face memorization.

The paper investigates how amyloid-beta accumulation in specific brain regions relates to memory deficits in preclinical Alzheimer's disease, finding a selective impact on temporal memory.

This study shows that NODDI metrics better predict Alzheimer's disease pathology and cognitive decline than traditional diffusion tensor imaging metrics in medial temporal lobe white matter.

The paper investigates two neuroinflammatory markers, YKL-40 and GFAP, and their associations with cerebrovascular injury, amyloid-beta, and downstream neurodegeneration in older adults without dementia.

This study finds that moderate-intensity physical activity improves overnight emotional memory retention in older adults, with benefits from both frequency and duration of activity.

The paper shows cerebrovascular pathology mediates the link between REM sleep hypoxemia and entorhinal cortical thickness, which is associated with impaired memory in older adults.

The paper shows that post-encoding awake sharp-wave/ripples (aSWRs) in the human amygdala and hippocampus predict better memory discrimination of emotional stimuli.

The paper investigates theta rhythm dynamics in human hippocampal-neocortical interactions during memory formation and retrieval, finding differential theta power and directional biases in communication.

This study examines how network integration and centrality in the medial temporal lobe during NREM sleep relate to emotional memory retention in older adults.

The paper identifies a pathological brain state in Alzheimer's disease linked to cognitive decline and neurodegeneration, suggesting it as a target for neuromodulation.

This study investigates whether the entorhinal-DG/CA3 pathway supports visual working memory of a simple surface feature using an orientation WM task and fMRI.

This study examines the relationship between white matter hyperintensities, medial temporal lobe volumes, and memory in older adults, finding that occipital hyperintensities are linked to reduced subregional volumes and worse memory performance.

The paper examines the relationship between entorhinal-hippocampal circuit integrity, mnemonic discrimination, and amyloid-β pathology in older adults using fMRI and PET.

The paper derives input-output transformation functions for hippocampal CA3 to CA1 synapses using Volterra expansion, revealing timing rules and differences between apical and basal dendrites.

This study shows that 20-40 Hz oscillations in CA1 reflect trial-specific processing of nonspatial sequence memory in rats.

This study shows that early life adversity in male mice alters reward circuit connectivity and leads to anhedonia in adulthood.

The paper investigates how uncinate fasciculus integrity relates to hippocampal subregion activity during emotional pattern separation and links this to memory performance.

The paper uses PET scans to identify brain amyloid patterns in individuals with Down syndrome that predict future dementia conversion.

The paper introduces an ANTs-based longitudinal cortical thickness pipeline and demonstrates its effectiveness in analyzing ADNI-1 data for detecting structural brain changes over time.

This paper investigates the use of florbetapir PET to predict dementia in adults with Down syndrome by examining amyloid accumulation and its relationship to AD pathology.

This study identifies hypoactivity in the anterolateral entorhinal cortex in older adults, linked to impaired object pattern separation, without changes in the posteromedial entorhinal cortex.