Mei-Fang Xiao

The paper identifies molecular programs coordinated with NPTX2 that distinguish cognitive resilience in AD pathology from non-pathological cognition and AD.

The paper investigates NPTX2 dynamics in aging rats to understand its role in cognitive aging and neurodegeneration, finding that successful cognitive aging is linked to increased NPTX2 levels and adaptive responses to memory tasks.

This study investigates the role of NPTX2 loss of function in sleep and circadian rhythm disruption, showing that NPTX2 KO mice exhibit disrupted circadian rhythms and sleep fragmentation.

This study identifies Nptx2 as a regulator of complement activity in the brain, showing its role in preventing microglial synapse elimination in health and disease.