BiochemistryThe EMBO JournalPeer-reviewed
Structural insight into binding site access and ligand recognition by human ABCB1
Devanshu Kurre, Phuoc Xuan Dang, Le Thi My Le…·Amer Alam
This study presents cryo-EM structures of human ABCB1 in different states, revealing structural asymmetry and TM4's role in substrate recognition and transport.