Author

Varun V. Gadkari

University of MichiganORCID 0000-0001-6145-3773Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex S. HolehouseiD· 1 shared Amer AlamiD· 1 shared Brandon T. RuotoloiD· 1 shared Devanshu KurreiD· 1 shared Emery T. UsheriD· 1 shared James C.A. BardwelliD· 1 shared Le Thi My LeiD· 1 shared Loïc SalmoniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Alex S. HolehouseORCID

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2 papers

Recent·Most cited

BiochemistryThe EMBO JournalPeer-reviewedJan 13, 2025

Structural insight into binding site access and ligand recognition by human ABCB1

Devanshu Kurre, Phuoc Xuan Dang, Le Thi My Le…·Amer Alam

This study presents cryo-EM structures of human ABCB1 in different states, revealing structural asymmetry and TM4's role in substrate recognition and transport.

25 citationstop 1%

humancryo-EM

𝕏 PostBluesky

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedNov 26, 2024

Molecular insights into the interaction between a disordered protein and a folded RNA

Rishav Mitra, Emery T. Usher, Selin Dedeoğlu…·James C.A. Bardwell

This study characterizes the RNA-binding properties of a disordered protein, SERF, and shows that binding to RNA causes modest global compaction without inducing structural changes in either molecule.

11 citations

proteomicsbiophysical modeling

𝕏 PostBluesky