Author

Le Thi My Le

University of MinnesotaORCID 0000-0002-0700-6064Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:cryo-EM· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Amer AlamiD· 1 shared Ann M. BodeiD· 1 shared Devanshu KurreiD· 1 shared Joohyun RyuiD· 1 shared Phuoc Xuan DangiD· 1 shared Preston M. McCourtiD· 1 shared Rafael Contreras-GalindoiD· 1 shared Souren PauliD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Amer AlamORCID

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2 papers

Recent·Most cited

Structural insight into binding site access and ligand recognition by human ABCB1

Devanshu Kurre, Phuoc Xuan Dang, Le Thi My Le, Varun V. Gadkari, Amer Alam

This study presents cryo-EM structures of human ABCB1 in different states, revealing structural asymmetry and TM4's role in substrate recognition and transport.

The EMBO Journal · Jan 13, 2025Peer-reviewedBiochemistry

Fyn-mediated phosphorylation of Menin disrupts telomere maintenance in stem cells

Souren Paul, Preston M. McCourt, Le Thi My Le, Joohyun Ryu, Wioletta Czaja, Ann M. Bode, Rafael Contreras-Galindo, Zigang Dong

This study shows that Fyn-mediated phosphorylation of Menin disrupts telomere maintenance in stem cells by altering Menin's interaction with telomerase components.

bioRxiv · Oct 4, 2023 · PreprintMolecular Biology