NeuroscienceNeuronPeer-reviewed
Integrated stress response associated with dark microglia promotes microglial lipogenesis and contributes to neurodegeneration
Anna G. Flury, Leen Aljayousi, Hye-Jin Park…·Pinar Ayata
The paper identifies a neurodegenerative microglia phenotype driven by the integrated stress response (ISR) and shows that inhibiting ISR ameliorates neurodegenerative pathologies in AD models.
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