Author
Icahn School of Medicine at Mount SinaiORCID 0000-0001-7621-832XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Travis E. Faust, Yi‐Han Lee, Ciara D. O’Connor…·Dorothy P. Schafer
This study shows microglia instruct astrocyte-synapse interactions via Wnt signaling, enabling microglia to remove synapses during activity-dependent remodeling.
Anna G. Flury, Leen Aljayousi, Hye-Jin Park…·Pinar Ayata
The paper identifies a neurodegenerative microglia phenotype driven by the integrated stress response (ISR) and shows that inhibiting ISR ameliorates neurodegenerative pathologies in AD models.
Veronika Kana, Fiona A. Desland, María Casanova-Acebes…·Miriam Mérad
This study shows that CSF-1 signaling is essential for cerebellar microglia identity and function, and its disruption causes motor and social behavior defects.
Prerana Shrestha, Pinar Ayata, Pedro Herrero-Vidal…·Eric Klann
The paper develops a chemogenetic tool to inhibit protein synthesis in specific neurons and shows it is required for long-term memory consolidation.
Georgia Gunner, Lucas Cheadle, Kasey M. Johnson…·Dorothy P. Schafer
This study shows that sensory lesioning causes microglia to eliminate synapses through ADAM10 and fractalkine signaling, revealing a neuron-to-microglia pathway for synaptic remodeling.