Author

Joseph Hamilton

UCL Queen Square Institute of NeurologyORCID 0000-0001-9592-529XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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2020-2026 · peak 1/yr

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Michael D. FlowerORCID

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2 papers

NeuroscienceNAR Molecular MedicinePeer-reviewedMar 30, 2026

This study shows disrupting the MSH3 Y245/K246 DNA binding pocket reduces CAG repeat expansion in Huntington's disease models.

DOI 10.1093/narmme/ugag031

NeurosciencebioRxivPreprintJul 23, 2020

This study shows that reducing huntingtin protein levels decreases somatic instability in CAG-expanded loci in both mouse models and human neurons.

8 citations