ImmunologybioRxivPreprint
Divergent regulation of STING-mediated innate immune responses by CBP and p300
Koteswara Rao Garikapati, Derek Van Booven, Mohammad Faraz Zafeer…·Gaofeng Wang
This study shows that CBP promotes STING-mediated transcription in the nucleus, while p300 suppresses STING signaling in the cytoplasm, with p300 inhibitors enhancing immune responses.
DOI 10.64898/2026.08.30.745803