Author

Ethan Creed

St. Jude Children's Research HospitalORCID 0009-0007-5785-4575Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Adam T. SmileyiD· 1 shared Alexandre ZanghelliniiD· 1 shared Alia Clark‐ElSayediD· 1 shared Andrew D. EllingtoniD· 1 shared Chau-Duy-Tam VoiD· 1 shared Elizabeth H. KelloggiD· 1 shared Hailey M. WallaceiD· 1 shared Kaila E. NayveltiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Adam T. SmileyORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 29, 2026

Programmable DNA integration with New-to-Nature tools using Computational Protein Design

Hailey M. Wallace, Seong Guk Park, Adam T. Smiley…·Elizabeth H. Kellogg

This paper introduces NovoCAST, a new RNA-guided transposon system designed through computational protein design, enabling efficient and programmable DNA integration in human cells.

1 citation

humanDNA methylation

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintJul 10, 2025

Comparing LigandMPNN and Directed Evolution for Altering the Effector-Binding Site in the RamR Transcription Factor

Alia Clark‐ElSayed, Ethan Creed, Kaila E. Nayvelt, Andrew D. Ellington

The paper compares LigandMPNN and directed evolution for redesigning the effector-binding site of the RamR transcription factor, finding limited overlap between the two methods' results.

DOI 10.1101/2025.07.10.663684

E. coliprotein structure

𝕏 PostBluesky