A pipeline for the reconstruction and evaluation of context-specific human metabolic models at a large-scale
Vítor Vieira, Jorge Ferreira, Miguel Rocha
The paper presents a pipeline for reconstructing and evaluating context-specific human metabolic models using multi-omics data, validated on cancer cell lines and showing improved gene essentiality predictions.
PLoS Computational Biology · Jun 24, 2022Peer-reviewedSystems Biology