Kristina Bennet Emdal

Tethering-mediated recruitment of pioneer factors by NuRD enables signal dependent gene activation and protects cell identity

The paper identifies NuRD's role in tethering pioneer factors like SOX2 to transcription sites, enhancing ERK-dependent gene activation and maintaining cell identity.

The Human Cell Line Phosphoproteome Atlas: A Deep Empirical Resource Revealing Kinase Activity Landscapes

The paper presents a comprehensive human phosphoproteome atlas with over 200,000 phosphosites, improving phosphoproteomics speed and accuracy, and identifies kinase activity patterns linked to drug sensitivity.

Spatiotemporal Proteomics Deciphers Functional Selectivity of EGFR ligands

The paper uses spatiotemporal proteomics to identify how different EGFR ligands induce distinct signaling outcomes, revealing key proteins and phosphorylation sites involved in endocytic fate and functional selectivity.

Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses

COSMOS integrates multi-omics data with prior knowledge to generate mechanistic hypotheses about biological processes in renal cell carcinoma.