BioengineeringNature CommunicationsPeer-reviewed
A Novel Engineered U7 Small Nuclear RNA Scaffold Greatly Increases in vitro and in vivo ADAR-Mediated Programmable RNA Base Editing
Susan M. Byrne, Stephen M. Burleigh, Robert Fragoza…·Adrian W. Briggs
This paper develops a novel U7 snRNA scaffold that significantly enhances ADAR-mediated RNA base editing in vitro and in vivo, achieving up to 76% editing efficiency in mouse models.
20 citationstop 3%