Author
University of WashingtonORCID 0000-0002-0266-6610Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Yuzhen Liu, Christopher D. McGann, Conor P. Herlihy…·Devin K. Schweppe
DNA O-MAP identifies molecular neighborhoods around specific genomic loci using programmable probes and proteomics.
Susan M. Byrne, Stephen M. Burleigh, Robert Fragoza…·Adrian W. Briggs
This paper develops a novel U7 snRNA scaffold that significantly enhances ADAR-mediated RNA base editing in vitro and in vivo, achieving up to 76% editing efficiency in mouse models.
Evan E. Kania, Sara Bianchi, Aidan M. Fenix…·David M Shechner
The paper uses O-MAP to study a cardiac-specific RNA factory around TTN RNA, revealing its chromatin interactions, RNA composition, and role of RBM20 in gene regulation.
Ashley F. Tsue, Evan E. Kania, Diana Q. Lei…·David M Shechner
The paper introduces O-MAP, a method for discovering RNA-interacting proteins, transcripts, and genomic loci in situ with high precision and without genetic manipulation.