Author

Megan A. Gura

Brown UniversityORCID 0000-0001-9635-4046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genetics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Kimberly A. Seymour· 3 shared Kimberly M. AbtiD· 3 shared Richard N. FreimaniD· 3 shared Myles A. Bartholomew· 2 shared Soňa RelovskáiD· 2 shared Alexis K. Gadson· 1 shared Anna Nixon· 1 shared Hanna E. Richman· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersGenetics

Kimberly A. Seymour

Mutual co-authors in cluster

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4 papers

Recent·Most cited

GeneticsbioRxivPreprintJan 6, 2025

Transcriptional Integration of Meiotic Prophase I Progression and Early Oocyte Differentiation

Kimberly M. Abt, Myles A. Bartholomew, Anna Nixon…·Richard N. Freiman

This study shows that TAF4b is essential for coordinating meiotic prophase I progression and early oocyte differentiation in mouse fetal oocytes.

DOI 10.1101/2025.01.06.631470

mousebulk RNA-seq

𝕏 PostBluesky

GeneticsFrontiers in Cell and Developmental BiologyPeer-reviewedOct 12, 2023

TAF4b Transcriptional Regulation During Cellular Quiescence of Developing Prospermatogonia

Megan A. Gura, Myles A. Bartholomew, Kimberly M. Abt…·Richard N. Freiman

This study identifies TAF4b's role in regulating transcription during quiescence of mouse prospermatogonia, showing it controls cell cycle genes and has sex-dependent and -independent effects on fertility.

4 citations

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologyBiology of ReproductionPeer-reviewedMay 3, 2022

The Requirement of Ubiquitin C-Terminal Hydrolase L1 (UCHL1) in Mouse Ovarian Development and Fertility

Morgan F. Woodman, Meghan C.H. Ozcan, Megan A. Gura…·Kathryn J. Grive

This study shows UCHL1 is essential for ovarian folliculogenesis, estrous cyclicity, and fertility in female mice.

16 citations

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedJan 19, 2022

TAF4b transcription networks regulating early oocyte differentiation

Megan A. Gura, Soňa Relovská, Kimberly M. Abt…·Richard N. Freiman

This study identifies TAF4b-regulated transcription networks in mouse oocytes, revealing its role in meiosis, chromatin structure, and X-linked gene expression.

27 citations

mousebulk RNA-seq

𝕏 PostBluesky