Author

Richard N. Freiman

Brown UniversityORCID 0000-0002-7269-3630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Kimberly A. Seymour· 3 shared Kimberly M. AbtiD· 3 shared Megan A. GuraiD· 3 shared Myles A. Bartholomew· 2 shared Soňa RelovskáiD· 2 shared Anna Nixon· 1 shared Hanna E. Richman· 1 shared Haskan KayaiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersGenetics

Kimberly A. Seymour

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Author profile →

3 papers

Recent·Most cited

Transcriptional Integration of Meiotic Prophase I Progression and Early Oocyte Differentiation

Kimberly M. Abt, Myles A. Bartholomew, Anna Nixon, Hanna E. Richman, Megan A. Gura, Kimberly A. Seymour, Richard N. Freiman

This study shows that TAF4b is essential for coordinating meiotic prophase I progression and early oocyte differentiation in mouse fetal oocytes.

bioRxiv · Jan 6, 2025 · PreprintGenetics

TAF4b Transcriptional Regulation During Cellular Quiescence of Developing Prospermatogonia

Megan A. Gura, Myles A. Bartholomew, Kimberly M. Abt, Soňa Relovská, Kimberly A. Seymour, Richard N. Freiman

This study identifies TAF4b's role in regulating transcription during quiescence of mouse prospermatogonia, showing it controls cell cycle genes and has sex-dependent and -independent effects on fertility.

Frontiers in Cell and Developmental Biology · Oct 12, 2023Peer-reviewedGenetics

TAF4b transcription networks regulating early oocyte differentiation

Megan A. Gura, Soňa Relovská, Kimberly M. Abt, Kimberly A. Seymour, Tong Wu, Haskan Kaya, James M. A. Turner, Thomas G. Fazzio, Richard N. Freiman

This study identifies TAF4b-regulated transcription networks in mouse oocytes, revealing its role in meiosis, chromatin structure, and X-linked gene expression.

Development · Jan 19, 2022Peer-reviewedDevelopmental Biology