Kimberly M. Abt

This study shows that intermittent heat exposure during mid-to-late gestation in mice leads to reduced anogenital distance and increased hypospadias in male embryos, without affecting gene expression in the fetal testis.

This study shows that TAF4b is essential for coordinating meiotic prophase I progression and early oocyte differentiation in mouse fetal oocytes.

This study identifies TAF4b's role in regulating transcription during quiescence of mouse prospermatogonia, showing it controls cell cycle genes and has sex-dependent and -independent effects on fertility.

This study identifies TAF4b-regulated transcription networks in mouse oocytes, revealing its role in meiosis, chromatin structure, and X-linked gene expression.

This study shows that reducing tau improves behavioural and transcriptional issues in a mouse model of Alzheimer’s disease, suggesting synaptic tau reduction could be a therapeutic strategy.