NeurosciencebioRxivPreprint
Tau modulates nuclear integrity, chromatin, and cholesterol synthesis genes via the nuclear envelope
Lisa Diez, Renata Ponce-Lina, Cagla Kilic…·Susanne Wegmann
This study shows that increased somatodendritic Tau interacts with nuclear envelope proteins, causing nuclear damage and altering gene expression related to AD and tauopathies.
2 citations