Cong Wang

This study shows that increased somatodendritic Tau interacts with nuclear envelope proteins, causing nuclear damage and altering gene expression related to AD and tauopathies.

The paper develops recombinant protein standards and a search engine for XL-MS, showing Scout outperforms existing tools in speed, sensitivity, and false-discovery rate control.

The paper introduces Mimosa, a Transformer-based model for miRNA target prediction that incorporates non-canonical base-pairing patterns, achieving better performance than traditional methods.

This paper introduces CLASP, a cross-link assisted spatial proteomics method, to map sub-organelle proteomes and membrane protein topology in human mitochondria.

The paper uses quantitative proteomics to identify CDK9-interacting proteins, revealing the HSP90-CDC37-P-TEFb complex's role in BETi-induced HIV-1 latency reactivation.