Dario Pfyffer

Centrally generated movement-related signals engage ipsilateral S1 finger representations after tetraplegia

This study shows that individuals with tetraplegia exhibit finger-specific brain activity in ipsilateral S1 without peripheral input, challenging the idea that somatotopic activity depends on sensory reafference.

Differential encoding of noxious heat and self-reported pain along corticospinal networks: a simultaneous spinal cord-brain fMRI study

This study uses simultaneous spinal cord-brain fMRI to show how nociceptive stimuli and pain perception are encoded in corticospinal networks, with spinal cord activity primarily reflecting stimulus temperature.

EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data

The paper introduces EPISeg, a deep learning model for automated spinal cord segmentation on gradient-echo EPI data, showing improved performance over existing methods.

Mapping Hand Function with Simultaneous Brain-Spinal Cord Functional MRI

This study uses simultaneous brain-spinal cord fMRI to map neural activity related to hand strength and dexterity, revealing graded activation and inhibition patterns across motor and sensory regions.

Finger somatotopy is preserved after tetraplegia but deteriorates over time

This study shows that somatosensory representations of paralyzed hands are preserved in SCI patients but deteriorate over time, suggesting potential for neuroprosthetic use despite sensory and motor loss.