Tae Kyung Kim

The paper describes an optimized Patch-seq technique for high-quality electrophysiological, morphological, and transcriptomic characterization of neurons, along with software tools for data acquisition and analysis.

The paper characterizes transcriptomic and physiological properties of GABAergic cortical neurons in mice, identifying 20 interneuron met-types with consistent features across modalities.

The paper develops enhancer viruses and a transgenic mouse line to enable combinatorial labeling of specific neuronal subclasses in the mouse cortex and human slices.

The paper identifies shared and distinct transcriptomic cell types in two mouse neocortical regions using scRNA-seq, showing most excitatory types are region-specific while inhibitory types are shared.