Andreas Wieland

This paper shows E2 activates the DNA damage response by displacing CIP2A from TOPBP1, promoting viral replication and cell proliferation through ATM activation and ATR inhibition.

The paper develops a multimodal profiling framework to analyze T cell phenotype and clonality in HNSCC tumors, revealing spatial and antigen-specific differences in T cell function.

This paper shows that CK2 phosphorylation of HPV16 E2 on serine 23 promotes interaction with TopBP1, which is critical for plasmid retention and HPV16 immortalization of keratinocytes.