Dawn Lisa DeMeo

The paper identifies sex-linked differences in colon cancer drug metabolism via gene regulatory network analysis, showing improved survival in females with higher pathway targeting.

The paper introduces a model-based clustering method to detect differentially variable microRNAs, outperforming the probe-wise F test and identifying 7 novel microRNAs in hepatocellular carcinoma.

This study analyzes gene regulation across 38 tissues to show that transcription factor-target connections are more tissue-specific than genes, and that tissue-specific genes are not highly targeted in their networks but occupy bottleneck positions.

The paper identifies ACVR1B as a candidate causal gene for emphysema distribution by integrating GWAS, eQTL, and epigenomic data.

The paper compares gene expression and regulatory patterns between cell lines and their source tissues, finding reduced expression levels and altered transcription factor regulation in cell lines.

The paper identifies sexual dimorphism in gene expression and regulatory networks across 31 human tissues using GTEx data, showing that many genes and networks are sex-specific.