Emrah Altındiş

Evolution of Insulin, Insulin-like Growth Factor, and Their Cognate Receptors in Vertebrates, Invertebrates, and Viruses

This study analyzes the evolutionary origins and molecular diversification of insulin, IGFs, and their receptors across vertebrates, invertebrates, and viruses, revealing lineage-specific adaptations and conserved features.

The Impact of Parabacteroides distasonis Colonization on Hosts' Microbiome, Metabolome, Immune Responses, and Diabetes Onset

This paper investigates how Parabacteroides distasonis colonization affects the microbiome, immune responses, and diabetes onset in NOD mice, finding it induces insulitis and activates specific T-cells without causing broad inflammation.

Sex-Specific Cytokine, Chemokine, and Growth Factor Signatures in T1D Patients and Progressors

This study identifies sex-specific cytokine, chemokine, and growth factor differences in T1D patients and progressors, highlighting potential implications for personalized treatment.

Viral Insulin/IGF-like Peptides Selectively Activate Host Insulin/IGF Signaling pathways during Grouper Iridovirus Infection

This study identifies GIV-VILP as a viral mimic of host insulin/IGF-1 that selectively activates the Akt/PI3K pathway during infection, enhancing viral replication.