Author

Juan Pablo Palavicini

The University of Texas at San Antonio Health Science CenterORCID 0000-0001-9667-8438Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 5

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Research Focus:differential expression· 3 Assay:proteomics· 3 Assay:spatial transcriptomics· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Xianlin HaniD· 4 shared Eduardo Gutierrez KuriiD· 3 shared Kevin F. BieniekiD· 3 shared Savannah Barannikov· 3 shared Gabriela Campos· 2 shared Hu WangiD· 2 shared Juliet Lynn Marie Garcia-Rogers· 2 shared Mark P. GoldbergiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Xianlin HanORCID

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5 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 30, 2026

Spatially resolved single-cell atlas reveals cortical glial reactivity associated with regions of neuronal growth programs in both hemispheres after stroke

Matthew R. Kenwood, Dene Betz, Eduardo Gutierrez Kuri…·Mark P. Goldberg

The paper uses spatial transcriptomics to show reactive glial populations are spatially associated with neuronal growth in both hemispheres after stroke.

DOI 10.64898/2026.10.26.761917

mousespatial transcriptomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 14, 2026

PLCγ2 deficiency compromises systemic immune tolerance and erodes myelin homeostasis while enhancing oxidative metabolism in the mouse brain

Eduardo Gutierrez Kuri, Juliet Lynn Marie Garcia-Rogers, Jaid Perez…·Juan Pablo Palavicini

This study investigates the effects of PLCγ2 deficiency in mice, showing impaired immune tolerance, myelin homeostasis disruption, and enhanced oxidative metabolism in the brain.

DOI 10.64898/2026.07.13.738356

mouseproteomics

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NeurosciencebioRxivPreprintNov 18, 2024

Microglia-Dependent and Independent Modulation of Brain Lipid Metabolism in Alzheimer's Disease Revealed by Pharmacological and Genetic Microglial Depletion

Ziying Xu, Sepideh Kiani Shabestari, Savannah Barannikov…·Xianlin Han

This study identifies microglia-dependent and independent mechanisms of lipid dysregulation in Alzheimer's disease using mouse models and lipidomics.

DOI 10.1101/2024.11.18.624173

mouseproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 6, 2023

Multi-omics analyses reveal novel effects of PLCγ2 deficiency in the mouse brain

Sarah C. Hopp, Juliet Lynn Marie Garcia-Rogers, Sabrina E. Smith…·Juan Pablo Palavicini

This study investigates the effects of PLCγ2 deficiency in mouse brains using multi-omics approaches, revealing sex-specific changes in lipid and gene expression that may link to Alzheimer's disease and aging.

4 citations

mouseproteomics

𝕏 PostBluesky

NeuroscienceFrontiers in EndocrinologyPeer-reviewedSep 23, 2020

Leptin Receptors in RIP-Cre25Mgn neurons Mediate Anti-Dyslipidemia Effects of Leptin in Insulin-Deficient Male Mice

Ashish Kumar Singha, Juan Pablo Palavicini, Meixia Pan…·Teppei Fujikawa

This study identifies RIP-Cre25Mgn neurons expressing leptin receptors as critical for leptin's anti-dyslipidemia and glucose-lowering effects in insulin-deficient mice.

10 citations

mouseexperimental assay

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