Author

Ziying Xu

The University of Texas at San Antonio Health Science CenterORCID 0000-0003-3725-7726Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ziying Xu1 paper · Johns Hopkins University

Biology Disciplines

Click to filter author papers

Physiology· 2 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 4 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:deconvolution· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

James F. NelsoniD· 2 shared Laurence T. MaeyensiD· 2 shared Nisi JiangiD· 2 shared Shangang ZhaoiD· 2 shared Xianlin HaniD· 2 shared Adam B. SalmoniD· 1 shared Bi‐Feng YuaniD· 1 shared Chanmin JoungiD· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

James F. NelsonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PhysiologybioRxivPreprintOct 24, 2026

Beneficial early, harmful later: age-dependent effects of testicular factors on male mortality

Laurence T. Maeyens, Nisi Jiang, Ziying Xu…·James F. Nelson

The paper shows that castration at different ages in mice affects male mortality differently, with later castration providing greater survival benefits and suggesting age-dependent effects of testicular factors on longevity.

DOI 10.64898/2026.10.19.760267

mouseexperimental assay

𝕏 PostBluesky

PhysiologybioRxivPreprintFeb 14, 2026

Non-enzymatic ABHD6 interacts with Akt-FoxO1 axis to regulate selective hepatic insulin resistance

Guannan Li, Laurence T. Maeyens, Jiyuan Yin…·Shangang Zhao

This study identifies a non-enzymatic role of ABHD6 in regulating selective hepatic insulin resistance and MASLD through interaction with the Akt-FoxO1 axis.

DOI 10.64898/2026.02.11.705361

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 18, 2024

Microglia-Dependent and Independent Modulation of Brain Lipid Metabolism in Alzheimer's Disease Revealed by Pharmacological and Genetic Microglial Depletion

Ziying Xu, Sepideh Kiani Shabestari, Savannah Barannikov…·Xianlin Han

This study identifies microglia-dependent and independent mechanisms of lipid dysregulation in Alzheimer's disease using mouse models and lipidomics.

DOI 10.1101/2024.11.18.624173

mouseproteomics

𝕏 PostBluesky

GeneticsbioRxivPreprintDec 21, 2017

Identification of methylation and hydroxymethylation haplotype blocks as distal regulatory elements aids in deconvolution of heterogeneous brain tissues

Qin Ma, Zhengzheng Xu, Huan Lu…·Weimin Ci

DOI 10.1101/237024

mouseDNA methylation

𝕏 PostBluesky