Molecular BiologyMolecular CellPeer-reviewed
Structure reveals mechanism of CRISPR RNA-guided nuclease recruitment and anti-CRISPR viral mimicry
MaryClare F. Rollins, Saikat Chowdhury, Joshua J. Carter…·Blake Wiedenheft
The paper presents the cryo-EM structure of the type I-F CRISPR surveillance complex and shows a conformational change that exposes a nuclease recruitment helix homologous to an anti-CRISPR protein.
99 citationstop 3%