Author
The University of Texas MD Anderson Cancer CenterORCID 0000-0002-0783-3959Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Saikat Chowdhury, Ichiaki Ito, Vinay K. Pattalachinti…·John Paul Shen
This study evaluates KRAS inhibitors in appendiceal adenocarcinoma models and patients, showing efficacy in reducing tumor growth and suggesting potential resistance mechanisms.
Hey Min Lee, Zhao Zheng, Alexey V. Sorokin…·Scott Kopetz
This study shows BET + MAPK inhibitors improve efficacy against BRAFV600E CRC by inducing epigenetic reprogramming and cellular plasticity through enhancer dynamics disruption.
Akash R. Boda, Irfan N. Bandey, Saikat Chowdhury…·Manisha Singh
This study investigates the effect of IL-1R1 blockade on CD40 agonist therapy in PDAC, finding it does not improve efficacy and worsens liver toxicity.
Benjamin Basanta, Saikat Chowdhury, Gabriel C. Lander, Danielle Ann Grotjahn
The paper introduces a user-guided refinement approach for subtomogram averaging to improve alignment of structurally complex macromolecular assemblies.
MaryClare F. Rollins, Saikat Chowdhury, Joshua J. Carter…·Blake Wiedenheft
The paper presents the cryo-EM structure of the type I-F CRISPR surveillance complex and shows a conformational change that exposes a nuclease recruitment helix homologous to an anti-CRISPR protein.