Amynah A. A. Pradhan

This paper evaluates the efficacy of PN6047, a novel DOR agonist, in preclinical headache models and finds it effectively reduces pain and prevents medication overuse headache.

This study shows that inhibiting PACAP-PAC1 receptors reduces opioid-induced chronic headache in mouse models by blocking PACAPergic mechanisms.

This study shows HDAC6 inhibition restores neuronal complexity in chronic migraine models, suggesting it as a potential therapeutic target.