Yaseen Awad-Igbaria

Mitochondrial Dysfunction is Part of a Novel Mechanism for Chemotherapy-Induced Neuropathic Pain

This study identifies persistent spinal mitochondrial dysfunction and increased mPTP susceptibility as features of chemotherapy-induced neuropathic pain and supports mitochondrial protection as a therapeutic strategy.

PN6047 Demonstrates Broad Preclinical Efficacy in Headache Models as a Novel Delta-Opioid Receptor Agonist

This paper evaluates the efficacy of PN6047, a novel DOR agonist, in preclinical headache models and finds it effectively reduces pain and prevents medication overuse headache.