Serapio M. Baca

This paper evaluates the efficacy of PN6047, a novel DOR agonist, in preclinical headache models and finds it effectively reduces pain and prevents medication overuse headache.

This study shows HDAC6 inhibition restores neuronal complexity in chronic migraine models, suggesting it as a potential therapeutic target.

This study shows that Fmr1KO mice have hyperexcitability and increased excitatory synaptic strength in the lateral amygdala, with reduced feedforward inhibition contributing to enhanced plasticity and E/I imbalance linked to anxiety disorders.

The paper identifies a subpopulation of fast-spiking Sst+ interneurons that mediate feedforward inhibition and gate plasticity in the basolateral amygdala.