The paper develops Quartet, a proteome reference material with built-in truths, to assess label-free proteomics reproducibility across platforms and labs.

43 citationstop 3%

proteomicsexperimental assay

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedOct 16, 2020

Standardization and Harmonization of Distributed Multi-National Proteotype Analysis supporting Precision Medicine Studies

Yue Xuan, Nicholas W. Bateman, Sébastien Gallien…·Thomas P. Conrads

This paper standardizes a proteotype analysis workflow across multiple international sites to enable distributed, reproducible proteomic data generation for precision medicine.

91 citationstop 3%

humanproteomics

𝕏 PostBluesky

BioinformaticsGenomics Proteomics & BioinformaticsPeer-reviewedApr 1, 2020

DPHL: A pan-human protein mass spectrometry library for robust biomarker discovery using Data-Independent Acquisition and Parallel Reaction Monitoring

Tiansheng Zhu, Yi Zhu, Yue Xuan…·Tiannan Guo

The paper introduces DPHL, a pan-human protein mass spectrometry library built using DIA and PRM, and demonstrates its utility in identifying differentially expressed proteins in prostate cancer and DLBCL.

94 citationstop 2%

humanproteomics

𝕏 PostBluesky