Prostate Cancer Reshapes the Secreted and Extracellular Vesicle Urinary Proteomes
Amanda Khoo, Meinusha Govindarajan, Zhuyu Qiu, Lydia Liu, Vladimir Ignatchenko, Matthew Waas, Andrew M. Macklin, Alexander F. A. Keszei, Sarah Neu, Brian P. Main, Lifang Yang, Raymond S. Lance, Michelle R. Downes, Oliver John Semmes, Danny Vesprini, , Thomas Kislinger
The paper quantifies secreted and extracellular vesicle (EV) urinary proteomes in men with and without prostate cancer, showing their stability and utility in distinguishing malignant from benign lesions.
Nature Communications · Jun 13, 2024Peer-reviewedSystems Biology