Amanda Khoo

Ancestry-Dependent Immunologic and Prognostic Effects Characterize the Prostate Cancer Urinary Proteome

The paper quantifies urinary proteome differences between Black and White prostate cancer patients, finding immune pathway dysregulation and aggressive cancer features in Black patients after controlling for age, PSA, and cISUP.

Pan-cancer N-glycoproteomic atlas of patient derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers

This paper uses N-glycoproteomics to analyze patient-derived xenografts, identifies FAT2 as a therapeutic target for head and neck cancers, and validates its role in tumor growth and CAR T cell activity.

Prostate Cancer Reshapes the Secreted and Extracellular Vesicle Urinary Proteomes

The paper quantifies secreted and extracellular vesicle (EV) urinary proteomes in men with and without prostate cancer, showing their stability and utility in distinguishing malignant from benign lesions.

Standardization and Harmonization of Distributed Multi-National Proteotype Analysis supporting Precision Medicine Studies

This paper standardizes a proteotype analysis workflow across multiple international sites to enable distributed, reproducible proteomic data generation for precision medicine.