Author

Tiansheng Zhu

Fudan UniversityORCID 0000-0002-7335-9087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Research Focus:database / resource· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:batch correction / integration· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Tiannan GuoiD· 4 shared Xiao YiiD· 4 shared Cong LuiD· 3 shared Guan RuaniD· 3 shared Jiang ZhuiD· 3 shared Liang YueiD· 3 shared Yaoting SuniD· 3 shared Connie R. JiméneziD· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBioinformatics

Tiannan GuoORCID

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4 papers

Recent·Most cited

DPHL v2: An updated and comprehensive DIA pan-human assay library for quantifying more than 14,000 proteins.

Zhangzhi Xue, Tiansheng Zhu, Fangfei Zhang, Cheng Zhang, Nan Xiang, Liujia Qian, Xiao Yi, Yaoting Sun, Wei Liu, Xue Cai, Linyan Wang, Xizhe Dai, Liang Yue, Lu Li, Thang V. Pham, , Tiannan Guo

DPHL v2 improves upon DPHL v1 by including semi-tryptic peptides and protein isoforms, increasing identified and dysregulated proteins in colorectal cancer analysis.

bioRxiv · Jan 7, 2023 · PreprintBioinformatics

BatchServer: a web server for batch effect evaluation, visualization and correction

Tiansheng Zhu, Rui Sun, Fangfei Zhang, Guo‐Bo Chen, Xiao Yi, Guan Ruan, Chunhui Yuan, Shuigeng Zhou, Tiannan Guo

BatchServer provides a web platform for evaluating, visualizing, and correcting batch effects in omics data using autoComBat, PVCA, and UMAP.

Journal of Proteome Research · Dec 18, 2020Peer-reviewedBioinformatics

DPHL: A pan-human protein mass spectrometry library for robust biomarker discovery using Data-Independent Acquisition and Parallel Reaction Monitoring

Tiansheng Zhu, Yi Zhu, Yue Xuan, Huanhuan Gao, Xue Cai, Sander R. Piersma, Thang V. Pham, Tim Schelfhorst, Richard R. de Haas, Irene V. Bijnsdorp, Rui Sun, Liang Yue, Guan Ruan, Qiushi Zhang, Mo Hu, , Tiannan Guo

The paper introduces DPHL, a pan-human protein mass spectrometry library built using DIA and PRM, and demonstrates its utility in identifying differentially expressed proteins in prostate cancer and DLBCL.

Genomics Proteomics & Bioinformatics · Apr 1, 2020Peer-reviewedBioinformatics

Identification of protein abundance changes in biopsy-level hepatocellular carcinoma tissues using PCT-SWATH

Yi Zhu, Jiang Zhu, Cong Lu, Qiushi Zhang, Wei Xie, Ping Sun, Xiaochuan Dong, Liang Yue, Yaoting Sun, Xiao Yi, Tiansheng Zhu, Guan Ruan, Ruedi H. Aebersold, Shiang Huang, Tiannan Guo

This study uses PCT-SWATH to analyze proteomic changes in HCC biopsy samples, identifying 23 upregulated pathways and 13 downregulated ones, with notable changes in virus-infection-related proteins in HBV+ patients.

PROTEOMICS - CLINICAL APPLICATIONS · Oct 26, 2018Peer-reviewedSystems Biology