This study measures blood biomarkers of neurodegeneration and inflammation in rhesus macaques across adulthood, finding age-related increases in NfL and IL-6 and a decline in Aβ42/Aβ40 ratio.

Experimental Gerontology · Mar 21, 2025Peer-reviewedPhysiology

Sexual differentiation of neural mechanisms of stress sensitivity during puberty

Emily C. Wright, Pei X. Luo, Hannah Cortez Zakharenkov, Alexandra Serna Godoy, Alyssa A. Lake, Zhana D. Prince, Shwetha Sekar, Hannah I. Culkin, Alison V. Ramirez, Tjien Dwyer, Amita Kapoor, Cody Corbett, Lin Tian, Andrew S. Fox, Brian C. Trainor

The paper shows that pubertal androgen exposure programs adult behavioral responses to social defeat stress, with effects mediated by the bed nucleus of the stria terminalis.

Proceedings of the National Academy of Sciences · Oct 17, 2023Peer-reviewedNeuroscience

Validation of a Commercial Radioimmunoassay for Measurement of Human Peripheral Oxytocin

Keenan Gerred, Amita Kapoor

This paper validates a commercial radioimmunoassay for measuring intact oxytocin in human urine, serum, and saliva, showing it is specific, sensitive, and reproducible.

bioRxiv · Mar 22, 2023 · PreprintNeuroscience