Author

Mona Alqazzaz

University of TorontoORCID 0000-0001-9730-2328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1 Approach:statistical model· 1

Frequent Co-Authors

Aiden M. Sababi· 1 shared C.H. ArrowsmithiD· 1 shared Costanza Ferrari BardileiD· 1 shared Dalia Baršytė-LovejoyiD· 1 shared David ShechteriD· 1 shared Felipe E. CiamponiiD· 1 shared Garrett Bullivant· 1 shared Gary D. BaderiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aiden M. Sababi

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintMar 14, 2024

PRMT5 is required for full-length HTT expression by repressing multiple proximal intronic polyadenylation sites

Mona Alqazzaz, Felipe E. Ciamponi, Jolene Caifeng Ho…·Panagiotis Prinos

This paper identifies PRMT5 as a regulator of HTT mRNA splicing and alternative polyadenylation, showing that its inhibition reduces full-length HTT protein levels by promoting premature termination and cleavage.

DOI 10.1101/2024.03.14.584861

humanmultiome

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