Coiled-coil-mediated phase separation of Spef1 for non-centrosomal microtubule organization and function
Jinqi Ren, Juyuan Liu, Dong Li…·Wei Feng
This study shows that Spef1 undergoes liquid-liquid phase separation to facilitate non-centrosomal microtubule assembly by enriching tubulins, with its coiled-coil domain mediating this process.