ImmunologybioRxivPreprint
MUC4-targeted CAR-T Cells Restrain Chemotherapy-resistant Colorectal Cancer
Avik Chattopadhyay, Erin C. O’Connor, Anna M. Tingler…·Leonardo M.R. Ferreira
This study demonstrates that MUC4-targeted CAR-T cells effectively eliminate chemotherapy-resistant CRC cells in vitro and reduce tumor burden in vivo, showing promise for treating chemoresistant colorectal cancer.